Nuclear-uptake nanodrug delivery system for drug-resistant cancer therapy
نویسندگان
چکیده
منابع مشابه
A Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy
The development of multidrug resistance (MDR) has become an increasingly serious problem in cancer therapy. The cell-membrane overexpression of P-glycoprotein (P-gp), which can actively efflux various anticancer drugs from the cell, is a major mechanism of MDR. Nuclear-uptake nanodrug delivery systems, which enable intranuclear release of anticancer drugs, are expected to address this challenge...
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ژورنال
عنوان ژورنال: Science China Chemistry
سال: 2015
ISSN: 1674-7291,1869-1870
DOI: 10.1007/s11426-015-5349-2